Huifeng Zhu Selected Research

catalpol

1/2022	Feasibility of Catalpol Intranasal Administration and Its Protective Effect on Acute Cerebral Ischemia in Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms.
1/2021	Network Pharmacology-Based Prediction of Catalpol and Mechanisms against Stroke.
12/2019	Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model.
7/2019	Catalpol may improve axonal growth via regulating miR-124 regulated PI3K/AKT/mTOR pathway in neurons after ischemia.
1/2019	Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway.
1/2019	Catalpol improves axonal outgrowth and reinnervation of injured sciatic nerve by activating Akt/mTOR pathway and regulating BDNF and PTEN expression.
1/2016	Antidiabetic and antioxidant effects of catalpol extracted from Rehmannia glutinosa (Di Huang) on rat diabetes induced by streptozotocin and high-fat, high-sugar feed.
1/2013	Catalpol Induces Neuroprotection and Prevents Memory Dysfunction through the Cholinergic System and BDNF.
12/2009	[Progress in studies of pharmacological action and mechanisms of catalpol on brain diease].

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Huifeng Zhu Research Topics

Disease

6	Stroke (Strokes) 01/2022 - 01/2013
5	Neoplasms (Cancer) 01/2021 - 02/2010
3	Brain Ischemia (Cerebral Ischemia) 01/2022 - 12/2009
2	Crush Injuries 01/2019 - 01/2019
2	Melanoma (Melanoma, Malignant) 01/2016 - 01/2016
2	Infarction (Infarctions) 01/2015 - 01/2013
2	Ovarian Neoplasms (Ovarian Cancer) 03/2010 - 02/2010
1	Neuroinflammatory Diseases 12/2022
1	Sepsis (Septicemia) 12/2022
1	Cognitive Dysfunction 12/2022
1	Brain Injuries (Brain Injury) 01/2022
1	Brain Edema (Cerebral Edema) 01/2022
1	Cerebral Infarction 01/2022
1	Hemolysis 01/2022
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2022
1	Inflammation (Inflammations) 01/2021
1	Ischemia 07/2019
1	Muscular Atrophy (Muscle Atrophy) 01/2019
1	Hyperlipidemias (Hyperlipidemia) 01/2016
1	Neoplasm Metastasis (Metastasis) 01/2016
1	Anemia 01/2016
1	Body Weight (Weight, Body) 01/2016
1	Reperfusion Injury 01/2015
1	Prostatic Neoplasms (Prostate Cancer) 03/2010
1	Osteosarcoma (Osteogenic Sarcoma) 03/2010
1	Carcinoma (Carcinomatosis) 02/2010
1	Thymoma (Thymic Carcinoma) 02/2010
1	Alzheimer Disease (Alzheimer's Disease) 12/2009
1	Virus Diseases (Viral Diseases) 11/2009
1	Infections 11/2009
1	Influenza in Birds (Avian Flu) 11/2009
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 10/2008

Drug/Important Bio-Agent (IBA)

9	catalpolIBA 01/2022 - 12/2009
4	MicroRNAs (MicroRNA)IBA 07/2019 - 11/2009
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 10/2008
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 12/2022
1	LipopolysaccharidesIBA 12/2022
1	Pharmaceutical PreparationsIBA 01/2022
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021
1	Linoleic Acid (Linoleate)IBA 01/2021
1	Nerve Growth Factors (Neurotrophins)IBA 01/2021
1	AntioxidantsIBA 01/2021
1	Thromboplastin (Tissue Factor)IBA 01/2016
1	Small Interfering RNA (siRNA)IBA 01/2016
1	cadherin 5IBA 01/2016
1	Thrombin FDA Link 01/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016
1	Triglycerides (Triacylglycerol)IBA 01/2016
1	HDL CholesterolIBA 01/2016
1	TetraspaninsIBA 01/2016
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 01/2016
1	Sijunzi decoctionIBA 01/2016
1	Fluorouracil (Carac)FDA LinkGeneric 01/2016
1	Protein Isoforms (Isoforms)IBA 01/2016
1	CholesterolIBA 01/2016
1	RNA Splicing FactorsIBA 01/2016
1	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2016
1	Blood Glucose (Blood Sugar)IBA 01/2016
1	ligustilideIBA 01/2015
1	Molecular Chaperones (Chaperone, Molecular)IBA 01/2015
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2015
1	EdaravoneIBA 01/2013
1	Cyclin-Dependent Kinase Inhibitor p16IBA 03/2010
1	Tumor Suppressor Protein p14ARF (p14ARF)IBA 03/2010
1	Messenger RNA (mRNA)IBA 03/2010
1	TOR Serine-Threonine KinasesIBA 02/2010
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 02/2010
1	rehmannia rootIBA 12/2009
1	Biological ProductsIBA 10/2008
1	Interleukin-2 (IL2)IBA 10/2008
1	Immunoglobulin Fab FragmentsIBA 10/2008
1	Immunoglobulin Idiotypes (Idiotype, Immunoglobulin)IBA 10/2008

Therapy/Procedure

2	Intranasal Administration 01/2022 - 01/2015
2	Intravenous Injections 01/2016 - 01/2016
1	Denervation 01/2019
1	Oral Administration 01/2016